1. Name: 陳 怡 成 Yi-Cheng Chen

    Email:chen15@mail.tcu.edu.tw

2. 分機: 7211

3. Education：

Ph.D University of London, 1992-1996

4. Current title：

Assistant Professor, Dept. of Medical Technology, Tzu Chi University

5. Employments:

Assistant Professor, Dept. Of Medical Technology, Tzu Chi University, 1998-now

Postdoctor, Institute of Biomedical Science, Sinica Academia, 1996-1998

6. Research background:

結構生物學

7. Research Interests:

1.Protein X-ray crystallography

2.NMR

3.Membrane protein-lipids interaction

8. Representative Publications：

• Chen Y and Wallace BA. Binding of alkaline cations to the double-helical form of gramicidin. Biophysical Journal 1996; 71:163-170 (SCI).
• Chen Y, Tucker A and Wallace BA. Solution structure of a parallel left-handed double-helical gramicidin-A determined by 2D ¹H NMR. Journal of Molecular Biology 1996; 264:757-769 (SCI).
• Chen Y and Wallace BA. Secondary solvent effects on the circular dichroism spectra of polypeptides in non-aqueous environments: influence of polarization effects on the far ultraviolet spectra of alamethicin. Biophysical Chemistry 1997; 65:65-74 (SCI).
• Chen Y and Wallace BA. The effects of calcium ions on double helical forms of gramicidin. European Biophysical Journal 1997; 26:299-306 (SCI).
• Chen Y and Wallace BA. Solvent effects on the conformation and far UV CD spectra of gramicidin. Biopolymers 1997; 42: 771-781 (SCI).
• Chang CF, Chen CP, Chen YC, Hom K, et al. The solution structure of a cytotoxic ribonuclease from the oocytes of Rana catesbeiana. Journal of Molecular Biology 1998; 283:231-244 (SCI).
• Gorbatyuk, Vitaly ya.; Chen, YC; Wu, Yung-Jean, Youle, Richard J.; Huang, Tai-huang (1999), Sequence specific 1H, 13C and 15N resonance assignements of recombinant Onconase/P-30 protein, J. Biomol. NMR, 15, 343-344 (SCI)
• Huang, H.-b.; Chen, YC; Tsai, L-h; Wang H-c; Lin F-M; Horiuchi, A.; Greengard, P.; Nairn. A. C.; Shiao, M-S & Lin T-H (2000) Backbone 1H, 13C and 15N resonance assignments of Inhibitor-2- a Protein Inhibitor of Protein Phosphatase-1, J. Biomol. NMR (SCI)
• Huang, H.B., Chen YC, A. Horiuchi, L.H. Tsai, H.T. Liu, C.L. Chyan, M.J. Hsieh, C.K. Liu, F.M. Lin, P. Greengard, A.C. Nairn, M.S. Shiao, T.H. Lin.(2001), Backbone ¹H, ¹⁵N, and ¹³C resonance assignments of ARPP-19” J. Biomol. NMR ,19, 383-384 (SCI).
• Chyan, C.L.,. Tang T. C, Chen YC,. Liu H.T,. Lin F.M, Liu C.K., Hsieh M.J.,. Shiao M.S,. Huang H.B,. Lin T.H. "Letter to the Editor: Backbone ¹H, ¹⁵N, and ¹³C resonance assignments of inhibitor-1 - a protein inhibitor of protein phosphatase-1" ,(2001) J. Biomol. NMR .
• Hsin-tzu Liu, Ta-hsien Lin, Hann-chorng Kuo, Yi-chen Chen, Huey-Jen Tsay, Hao-Hsuan Jeng, Pai-Chi Tsai, Fu-kai Shie, Ji-hsiung Chen, and Hsien-bin Huang. “Identification of the Alternative Splice Products Encoded by the Human Protein Phosphatase Inhibitor-1 Gene.” (2002) Biochemical and Biophysical Reasearch Communications 291,1293-1296. (in press)